In this paper, we study the problem of knowledge-intensive text-to-SQL, in which domain knowledge is necessary to parse expert questions into SQL queries over domain-specific tables. We formalize this scenario by building a new Chinese benchmark KnowSQL consisting of domain-specific questions covering various domains. We then address this problem by presenting formulaic knowledge, rather than by annotating additional data examples. More concretely, we construct a formulaic knowledge bank as a domain knowledge base and propose a framework (ReGrouP) to leverage this formulaic knowledge during parsing. Experiments using ReGrouP demonstrate a significant 28.2% improvement overall on KnowSQL.

Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet, a supervised deep-learning model to predict the fitness for protein mutants by leveraging both sequence and structure information, and exploiting attention mechanism. Our model integrates local evolutionary context from homologous sequences, the global evolutionary context encoding rich semantic from the universal protein sequence space and the structure information accounting for the microenvironment around each residue in a protein. We show that SESNet outperforms state-of-the-art models for predicting the sequence-function relationship on 26 deep mutational scanning datasets. More importantly, we propose a data augmentation strategy by leveraging the data from unsupervised models to pre-train our model. After that, our model can achieve strikingly high accuracy in prediction of the fitness of protein mutants, especially for the higher order variants (> 4 mutation sites), when finetuned by using only a small number of experimental mutation data (<50). The strategy proposed is of great practical value as the required experimental effort, i.e., producing a few tens of experimental mutation data on a given protein, is generally affordable by an ordinary biochemical group and can be applied on almost any protein.

Text-to-SQL semantic parsing is an important NLP task, which greatly facilitates the interaction between users and the database and becomes the key component in many human-computer interaction systems. Much recent progress in text-to-SQL has been driven by large-scale datasets, but most of them are centered on English. In this work, we present MultiSpider, the largest multilingual text-to-SQL dataset which covers seven languages (English, German, French, Spanish, Japanese, Chinese, and Vietnamese). Upon MultiSpider, we further identify the lexical and structural challenges of text-to-SQL (caused by specific language properties and dialect sayings) and their intensity across different languages. Experimental results under three typical settings (zero-shot, monolingual and multilingual) reveal a 6.1% absolute drop in accuracy in non-English languages. Qualitative and quantitative analyses are conducted to understand the reason for the performance drop of each language. Besides the dataset, we also propose a simple schema augmentation framework SAVe (Schema-Augmentation-with-Verification), which significantly boosts the overall performance by about 1.8% and closes the 29.5% performance gap across languages.

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep learning methods, some models with good performance have emerged, but the generalization ability should be further strengthened. In this paper, we propose a two-stage mitosis segmentation and classification method, named SCMitosis. Firstly, the segmentation performance with a high recall rate is achieved by the proposed depthwise separable convolution residual block and channel-spatial attention gate. Then, a classification network is cascaded to further improve the detection performance of mitosis nuclei. The proposed model is verified on the ICPR 2012 dataset, and the highest F-score value of 0.8687 is obtained compared with the current state-of-the-art algorithms. In addition, the model also achieves good performance on GZMH dataset, which is prepared by our group and will be firstly released with the publication of this paper. The code will be available at: https://github.com/antifen/mitosis-nuclei-segmentation.

A key feature of federated learning (FL) is to preserve the data privacy of end users. However, there still exist potential privacy leakage in exchanging gradients under FL. As a result, recent research often explores the differential privacy (DP) approaches to add noises to the computing results to address privacy concerns with low overheads, which however degrade the model performance. In this paper, we strike the balance of data privacy and efficiency by utilizing the pervasive social connections between users. Specifically, we propose SCFL, a novel Social-aware Clustered Federated Learning scheme, where mutually trusted individuals can freely form a social cluster and aggregate their raw model updates (e.g., gradients) inside each cluster before uploading to the cloud for global aggregation. By mixing model updates in a social group, adversaries can only eavesdrop the social-layer combined results, but not the privacy of individuals. We unfold the design of SCFL in three steps. \emph{i) Stable social cluster formation. Considering users' heterogeneous training samples and data distributions, we formulate the optimal social cluster formation problem as a federation game and devise a fair revenue allocation mechanism to resist free-riders. ii) Differentiated trust-privacy mapping}. For the clusters with low mutual trust, we design a customizable privacy preservation mechanism to adaptively sanitize participants' model updates depending on social trust degrees. iii) Distributed convergence}. A distributed two-sided matching algorithm is devised to attain an optimized disjoint partition with Nash-stable convergence. Experiments on Facebook network and MNIST/CIFAR-10 datasets validate that our SCFL can effectively enhance learning utility, improve user payoff, and enforce customizable privacy protection.

A computational graph in a deep neural network (DNN) denotes a specific data flow diagram (DFD) composed of many tensors and operators. Existing toolkits for visualizing computational graphs are not applicable when the structure is highly complicated and large-scale (e.g., BERT [1]). To address this problem, we propose leveraging a suite of visual simplification techniques, including a cycle-removing method, a module-based edge-pruning algorithm, and an isomorphic subgraph stacking strategy. We design and implement an interactive visualization system that is suitable for computational graphs with up to 10 thousand elements. Experimental results and usage scenarios demonstrate that our tool reduces 60% elements on average and hence enhances the performance for recognizing and diagnosing DNN models. Our contributions are integrated into an open-source DNN visualization toolkit, namely, MindInsight [2].

Vision-Language Pre-Training (VLP) has shown promising capabilities to align image and text pairs, facilitating a broad variety of cross-modal learning tasks. However, we observe that VLP models often lack the visual grounding/localization capability which is critical for many downstream tasks such as visual reasoning. In this work, we propose a novel Position-guided Text Prompt (PTP) paradigm to enhance the visual grounding ability of cross-modal models trained with VLP. Specifically, in the VLP phase, PTP divides the image into $N\times N$ blocks, and identifies the objects in each block through the widely used object detector in VLP. It then reformulates the visual grounding task into a fill-in-the-blank problem given a PTP by encouraging the model to predict the objects in the given blocks or regress the blocks of a given object, e.g. filling `P" or ``O" in aPTP ``The block P has a O". This mechanism improves the visual grounding capability of VLP models and thus helps them better handle various downstream tasks. By introducing PTP into several state-of-the-art VLP frameworks, we observe consistently significant improvements across representative cross-modal learning model architectures and several benchmarks, e.g. zero-shot Flickr30K Retrieval (+4.8 in average recall@1) for ViLT \cite{vilt} baseline, and COCO Captioning (+5.3 in CIDEr) for SOTA BLIP \cite{blip} baseline. Moreover, PTP achieves comparable results with object-detector based methods, and much faster inference speed since PTP discards its object detector for inference while the later cannot. Our code and pre-trained weight will be released at \url{https://github.com/sail-sg/ptp}.

Aspect or query-based summarization has recently caught more attention, as it can generate differentiated summaries based on users' interests. However, the current dataset for aspect or query-based summarization either focuses on specific domains, contains relatively small-scale instances, or includes only a few aspect types. Such limitations hinder further explorations in this direction. In this work, we take advantage of crowd-sourcing knowledge on Wikipedia.org and automatically create a high-quality, large-scale open-domain aspect-based summarization dataset named OASum, which contains more than 3.7 million instances with around 1 million different aspects on 2 million Wikipedia pages. We provide benchmark results on OAsum and demonstrate its ability for diverse aspect-based summarization generation. To overcome the data scarcity problem on specific domains, we also perform zero-shot, few-shot, and fine-tuning on seven downstream datasets. Specifically, zero/few-shot and fine-tuning results show that the model pre-trained on our corpus demonstrates a strong aspect or query-focused generation ability compared with the backbone model. Our dataset and pre-trained checkpoints are publicly available.

Recently, there has been increasing interest in synthesizing data to improve downstream text-to-SQL tasks. In this paper, we first examined the existing synthesized datasets and discovered that state-of-the-art text-to-SQL algorithms did not further improve on popular benchmarks when trained with augmented synthetic data. We observed two shortcomings: illogical synthetic SQL queries from independent column sampling and arbitrary table joins. To address these issues, we propose a novel synthesis framework that incorporates key relationships from schema, imposes strong typing, and conducts schema-distance-weighted column sampling. We also adopt an intermediate representation (IR) for the SQL-to-text task to further improve the quality of the generated natural language questions. When existing powerful semantic parsers are pre-finetuned on our high-quality synthesized data, our experiments show that these models have significant accuracy boosts on popular benchmarks, including new state-of-the-art performance on Spider.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.